lifex-cfd: An open-source computational fluid dynamics solver for cardiovascular applications
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In this project we numerically simulate electrophysiological models for cardiac applications by means of Isogeometric Analysis. Specifically, we aim at understanding the advantages of using high order continuous NURBS (Non-UniformRational B-Splines) basis ...
Blood flow in the arterial circulation induces hemodynamic forces that play an important role in various forms of vascular diseases. Temporal variation of the wall shear stress seems to play a significant role in atherogenesis and plaque stability. Flow in ...
The simulation of the physiological loading situation of arteries with moderate atherosclerotic plaque may provide additional indicators for medical doctors to estimate if the plaque is likely to rupture and if surgical intervention is required. In particu ...
International Center for Numerical Methods in Engineeering (CIMNE)2014
Isogeometric analysis (IGA) is a computational methodology recently developed to numerically approximate Partial Differential Equation (PDEs). It is based on the isogeometric paradigm, for which the same basis functions used to represent the geometry are t ...
We consider the fluid-structure interaction problem arising in haemodynamic applications. The finite elasticity equations for the vessel are written in Lagrangian form, while the Navier-Stokes equations for the blood in Arbitrary Lagrangian Eulerian form. ...
Cardiovascular diseases are the first cause of death in industrialized countries. It is now widely established that blood fluid dynamics and its interaction with the vascular wall play an essential role in the development and evolution of vascular patholog ...
Accuracy is critical if we are to trust simulation predictions. In settings such as fluid-structure interaction, it is all the more important to obtain reliable results to understand, for example, the impact of pathologies on blood flows in the cardiovascu ...
A geometrical multiscale model for blood flow through an ideal left ventricle and the main arteries is presented. The blood flow in the three-dimensional idealized left ventricle is solved through a monolithic fluid-structure interaction solver. To account ...
Pluripotent stem cell-seeded cardiopatches hold promise for in situ regeneration of infarcted hearts. Here, we describe a novel cardiopatch based on bone morphogenetic protein 2-primed cardiac-committed mouse embryonic stem cells, embedded into biodegradab ...
In this thesis we address the numerical approximation of the incompressible Navier-Stokes equations evolving in a moving domain with the spectral element method and high order time integrators. First, we present the spectral element method and the basic to ...