Climbing into their Skin to Understand Contextual Protein-Protein Associations and Localizations: Functional Investigations in Transgenic Live Model Organisms
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The sequencing of genomes of several organisms and advances in high throughput technologies for transcriptome and proteome anal. has allowed detailed mechanistic studies of transcription and translation using math. frameworks that allow integration of both ...
Translation is a central cellular process in every organism and understanding translation from the systems (genome-wide) perspective is very important for medical and biochem. engineering applications. Moreover, recent advances in cell-wide monitoring tool ...
A review with 30 refs. Cellular engineering relies on the ability to decipher the genetic basis of various phenotypes. Emerging technologies for analyzing the biol. function of the information encoded in the genome of particular organisms and/or tissues fo ...
PROSITE is a compilation of sites and patterns found in protein sequences; it can be used as a method of determining the function of uncharacterized proteins translated from genomic or cDNA sequences. ...