Publication
Fluorescent fatty acid conjugates for live cell imaging of peroxisomes
Publications associées (36)
Reference Maps of Human ES and iPS Cell Variation Enable High-Throughput Characterization of Pluripotent Cell Lines
The developmental potential of human pluripotent stem cells suggests that they can produce disease-relevant cell types for biomedical research. However, substantial variation has been reported among pluripotent cell lines, which could affect their utility ...
20112D Stem Cell Culture on Microfluidic Generated Hydrogel Beads
Stem cells capacity to self-renew and differentiate into specialized cell types, endow them with great promises in regenerative medicine. It is believed that the stem cells microenvironment plays a significant role in regulating their fate. However, with e ...
2011Definition of in Vitro Microenvironments to Characterize and Control Pancreatic Progenitor Expansion and Differentiation
The pancreas plays a central role in metabolism. The exocrine pancreas, composed of ductal and acinar cells, secretes and delivers digestive enzymes into the duodenum where they contribute to food digestion. The endocrine pancreas, constituted by the islet ...
EPFL2011Visualization of proprotein convertase activity in living cells and tissues
The invention relates to a system for detecting the presence of a convertase cleaving activity, the system comprising a molecule comprising a proteolytic cleavage site with the amino acid sequence -R-X1-X2-R-, wherein R represents the amino acid arginine, ...
2011A Novel 3D hydrogel based microfluidic cell culture platform
Breakthroughs in health care over the coming decades may well consist of cell based therapeutics, potentially allowing the repair and replacement of damaged tissues and organs. Recently developed induced pluripotency methods as well as advances in stem cel ...
2009Tissue engineering of the bladder
Stem cell use in bladder tissue engineering is a recently addressed area of investigation that has generated excitement as a novel way to restore and regenerate lost or damaged urinary bladder tissue. The remodelling of smooth muscle plays a significant ro ...
EPFL2009The role of CITED2 in human embryonic stem cells
Human embryonic stem (hES) cells can self-renew in culture and differentiate into cells of all three germ layers. Identification of regulators of the self-renewal versus differentiation decisions in hES cells will facilitate manipulation of these cells. Se ...
2009Stem cell-based cardiovascular tissue engineering
Cardiovascular diseases, including myocardial infarction, are the leading cause of death worldwide for both men and women. Current therapies are limited by the restricted intrinsic regeneration capacity of the heart and by the lack of organs for transplant ...
EPFL2009A novel cell culture approach for tissue engineering based on surface expansion
Most tissue engineering approaches include the delivery of reparative cells to a damaged host tissue. Generally these cells are sought to be of a stem cell character since they retain a high potential for proliferation and differentiation into diverse phen ...
EPFL2008The role of the phosphoinositides at the Golgi complex
Eukaryotic cells are organized into a complex system of subcompartments, each with its distinct protein and lipid composition. A continuous flux of membranes crosses these compartments, and in some cases direct connections exist between the different organ ...
2007