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Bactericidal effect of tetracycline in E. coli strain ED1a may be associated with ribosome dysfunction

Publications associées (57)

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Unravelling the collateral damage of antibiotics on gut bacteria

Camille Véronique Bernadette Goemans

Antibiotics are used to fight pathogens but also target commensal bacteria, disturbing the composition of gut microbiota and causing dysbiosis and disease1. Despite this well-known collateral damage, the activity spectrum of different antibiotic classes on ...

2021

Fast spreading antimicrobial resistance (AMR) is an emerging major public health issue. New therapeutic and diagnostic paradigms must be implemented to counteract this evolution. In this respect, fast antimicrobial susceptibility testing (AST) plays an imp ...

EPFL2021

Microtissue models for studying the dynamics of host-pathogen interactions in the urinary bladder

Kunal Sharma

Urinary tract infections (UTIs) are amongst the most common bacterial infections and are the second-most frequent reason for antibiotic prescriptions. Moreover, in about 25% of all treated cases, recurrence of infection occurs. Uropathogenic Escherichia co ...

EPFL2021

Antimicrobial susceptibility testing by measuring bacterial oxygen consumption on an integrated platform

Martinus Gijs, Thomas Lehnert, Yang Liu

Cellular respiration is a fundamental feature of metabolic activity and oxygen consumption can be considered as a reliable indicator of bacterial aerobic respiration, including for facultative anaerobic bacteria like E. coli. Addressing the emerging global ...

ROYAL SOC CHEMISTRY2021

Revealing Antibiotic Tolerance of the Mycobacterium smegmatis Xanthine/Uracil Permease Mutant Using Microfluidics and Single-Cell Analysis

John McKinney, Neeraj Dhar, Meltem Elitas

To reveal rare phenotypes in bacterial populations, conventional microbiology tools should be advanced to generate rapid, quantitative, accurate, and high-throughput data. The main drawbacks of widely used traditional methods for antibiotic studies include ...

MDPI2021

Nanomotion Detection-Based Rapid Antibiotic Susceptibility Testing

Sandor Kasas, María Inés Villalba, Anton Malovichko

Rapid antibiotic susceptibility testing (AST) could play a major role in fighting multidrug-resistant bacteria. Recently, it was discovered that all living organisms oscillate in the range of nanometers and that these oscillations, referred to as nanomoti ...

2021

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Investigating and understanding dynamic biofilm growth mechanisms is challenging, often because state-of-theart optical characterization tools provide limited information. Micrometric electrochemical imaging of Escherichia coli biofilms using Soft-Probe-Sc ...

2021

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Investigating and understanding dynamic biofilm growth mechanisms is challenging, often because state-of-the-art optical characterization tools provide limited information. Micrometric electrochemical imaging of Escherichia coli biofilms using Soft-Probe-S ...

2021

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Fast spreading of antimicrobial resistance is now considered a major global health threat. New technologies are required, enabling rapid diagnostics of bacterial infection combined with fast antimicrobial susceptibility testing (AST) for evaluating the eff ...

ROYAL SOC CHEMISTRY2020

Resistance to disinfection agents: Adaptation of P. aeruginosa to sub inhibitory concentrations of quaternary ammonium compounds (QACs)

Urs von Gunten, Florian Frédéric Vincent Breider, Leonardo Venturelli, Margaux Océane Voumard

Quaternary ammonium compounds (QACs) are among the most used disinfection agents in consumer products and in industrial applications. Because of their poor biodegradabil ity, after use, they will persist in technical and natural aquatic systems at sub - in ...

2019