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Objectives(i) To assess the effects of mechanical overloading on implant integration in rat tibiae, and (ii) to numerically predict peri-implant bone adaptation. Materials and methodsTranscutaneous titanium implants were simultaneously placed into both tib ...
In this study we present a photocrosslinkable and layerable hydrogel based on decellularized extracellular matrix (dECM) intended for in vitromodels of cartilage tissue formation. dECM can provide cellular environments that are close to the native tissue s ...
Excessive interfacial micromotion endangers the implant primary stability by favoring the formation of a fibrous tissue layer at the bone-implant interface. It was recently proposed that implant micromotion induces fluid flow in the granulation tissue that ...
Background: orthopaedic surgeons often face clinical situations where improved screw holding power in cancellous bone is needed. Injectable calcium phosphate cements are one option to enhance fixation. Methods: paired screw pullout tests were undertaken in ...
The reliable assessment of craniofacial morphological changes during growth requires invariant regions for image registration. As these regions have not yet been identified in three dimensions, intra-osseous implants are required as fiducial markers for th ...
A good fixation of osteosynthesis implants is crucial for a successful bone healing but often difficult to achieve in osteoporotic patients. One possible solution to this issue is the local delivery of bisphosphonates in direct proximity to the implants, A ...
Several treatments have been developed for treating bone fractures as they are very common events. Amongst other new strategies, synthetic bone substitutes present a very high potential therapy because they lower the risk of infection and rejection. Moreov ...
Osteoporosis is a major health problem in our aging society. This metabolic disease, which is characterized by a deterioration of the bone microarchitecture and a significant loss of bone mass, is affecting a rising number of mostly elderly patients. The m ...
A nanostructured coating layer on titanium implants, able to improve their integration into bones and to protect against the harsh conditions of body fluids, was obtained by Ion Plating Plasma Assisted, a method suitable for industrial applications. A tita ...
A good implant primary stability is closely associated with long-term success of total hip arthroplasty. Excessive interfacial micromotion around the femoral component after cementless hip replacement is related to aseptic loosening of the stem and affects ...