Protocol for the PreventIT feasibility randomised controlled trial of a lifestyle-integrated exercise intervention in young older adults

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High spatial resolution dataset of La Mobiliere insurance customers

Claudia Rebeca Binder Signer, Emanuele Massaro

We present the La Mobiliere insurance customers dataset: a 12-year-long longitudinal collection of data on policies of customers of the Swiss insurance company La Mobiliere. To preserve the privacy of La Mobiliere customers, we propose the data aggregated ...

NATURE PORTFOLIO2022

Data Privacy Concerns as a Source of Resistance to Complete Mobile Data Collection Tasks Via a Smartphone App

Daniel Gatica-Perez

Smartphones present many interesting opportunities for survey research, particularly through the use of mobile data collection applications (apps). There is still much to learn, however, about how to integrate apps in general population surveys. Recent stu ...

OXFORD UNIV PRESS INC2022

Molecular Regulation of Muscle Stem Cell Fate during Skeletal Muscle Regeneration and Aging

Sara Ancel

Muscle stem cells (MuSCs) are the primary source of myogenic progenitors during muscle repair and are essential for the long-term regenerative capacity of skeletal muscle. Following myofiber injury, MuSCs transition from a quiescent to an activated state, ...

EPFL2022

The effects of time-restricted eating and weight loss on bone metabolism and health: a 6-month randomized controlled trial

Nicholas Edward Phillips, Alexandra Hemmer

Objective This study explored the impact of time-restricted eating (TRE) versus standard dietary advice (SDA) on bone health. Methods Adults with >= 1 component of metabolic syndrome were randomized to TRE (ad libitum eating within 12 hours) or SDA (food p ...

WILEY2022

The Future of Civic Technologies for the Involvement of Citizens in Urban Planning: 3D Urban Participatory e-Planning in the Spotlight

Thibaud Nicolas Chassin

The development of sustainable urban projects is crucial to address the challenges of the growing population living in cities. Facing complex decision-making and increasing expectations from inhabitants, local institutions are gradually becoming open to co ...

EPFL2022

Impact of the Natural Compound Urolithin A on Health, Disease, and Aging

Johan Auwerx, Pénélope Andreux, Davide D'Amico, Pamela Solange Valdés Undurraga, Anurag Singh

Urolithin A (UA) is a natural compound produced by gut bacteria from ingested ellagitannins (ETs) and ellagic acid (EA), complex polyphenols abundant in foods such as pomegranate, berries, and nuts. UA was discovered 40 years ago, but only recently has its ...

2021

Identifying a Motivational Profile for Older Adults Towards Increased Physical Activity

Pearl Pu Faltings, Yuan Lu

Personalizing behavior change (BC) strategies to motivate increased physical activity is especially important for the diverse older adult population. However, there is a lack of knowledge about how to profile older users to most effectively personalize BC ...

2021

Stabilization of cultural innovations depends on population density: Testing an epidemiological model of cultural evolution against a global dataset of rock art sites and climate-based estimates of ancient population densities

John Richard Walker, Taylor Howard Newton, Francesco Casalegno

Demographic models of human cultural evolution have high explanatory potential but weak empirical support. Here we use a global dataset of rock art sites and climate and genetics-based estimates of ancient population densities to test a new model based on ...

2021

Acute RyR1 Ca2+ leak enhances NADH-linked mitochondrial respiratory capacity

Johan Auwerx, Umberto De Marchi, Tanes Imamura de Lima

Sustained ryanodine receptor (RyR) Ca2+ leak is associated with pathological conditions such as heart failure or skeletal muscle weakness. We report that a single session of sprint interval training (SIT), but not of moderate intensity continuous training ...

Nature Portfolio2021

The Effects of Time-Restricted Eating versus Standard Dietary Advice on Weight, Metabolic Health and the Consumption of Processed Food: A Pragmatic Randomised Controlled Trial in Community-Based Adults

Felix Naef, Nicholas Edward Phillips

Weight loss is key to controlling the increasing prevalence of metabolic syndrome (MS) and its components, i.e., central obesity, hypertension, prediabetes and dyslipidaemia. The goals of our study were two-fold. First, we characterised the relationships b ...

2021

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