Privacy-enhancing technologies for medical tests using genomic data

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Inborn errors of type I interferon immunity in patients with symptomatic acute hepatitis E

Jacques Fellay

Background and Aims:The clinical spectrum of human infection by HEV ranges from asymptomatic to severe acute hepatitis. Furthermore, HEV can cause diverse neurological manifestations, especially Parsonage-Turner syndrome. Here, we used a large-scale human ...

Lippincott Williams & Wilkins2023

Optimised set of oligonucleotides for bulk rna barcoding and sequencing

Bart Deplancke, Vincent Roland Julien Gardeux, Riccardo Dainese, Daniel Alpern

The present invention relates generally to the field of nucleic acid sequencing and provides oligonucleotide molecules and barcodes contained therein. These oligonucleotide molecules and barcodes molecules are useful in sequencing to identify and resolve e ...

2023

Making Classical (Threshold) Signatures Post-quantum for Single Use on a Public Ledger

Serge Vaudenay, Laurane Chloé Angélina Marco, Abdullah Talayhan

The Bitcoin architecture heavily relies on the ECDSA signature scheme which is broken by quantum adversaries as the secret key can be computed from the public key in quantum polynomial time. To mitigate this attack, bitcoins can be paid to the hash of a pu ...

2023

Systematic benchmarking of single-cell ATAC-sequencing protocols

Bart Deplancke, Jörn Pezoldt, Camille Lucie Germaine Lambert

Benchmarking of scATAC-seq protocols demonstrates the effects of data quality on downstream analyses. ...

NATURE PORTFOLIO2023

Security in the Presence of Quantum Adversaries

Khashayar Barooti

With the looming threat of large-scale quantum computers, a fair portion of recent cryptographic research has focused on examining cryptographic primitives from the perspective of a quantum adversary. Shor's 1994 result revealed that quantum computers can ...

EPFL2023

Multiomic analysis of HER2-enriched and AR-positive breast carcinoma with apocrine differentiation and an oligometastatic course: a case report

Andrea Cavalli

Breast carcinoma is the most prevalent cancer among women globally. It has variable clinical courses depending on the stage and clinical-biological features. This case report describes a 56-year-old female with invasive breast cancer without estrogen or pr ...

FRONTIERS MEDIA SA2023

Modeling, analysis, and design of complex biological networks

Mohammadomid Oftadeh

Automating experimental procedures has resulted in an unprecedented increase in the volume of generated data, which, in turn, has caused an accumulation of unprocessed data. As a result, the need to develop tools to analyze data systematically has been ris ...

EPFL2023

Multienzyme deep learning models improve peptide de novo sequencing by mass spectrometry proteomics

Hamed Khakzad

Author summaryIn recent years, the application of deep learning represented a breakthrough in the mass spectrometry (MS) field by improving the assignment of the correct sequence of amino acids from observable MS spectra without prior knowledge, also known ...

PUBLIC LIBRARY SCIENCE2023

Automatic and high-precision microseismic monitoring of progressive failure prior, during, and after tunnel excavation

Brice Tanguy Alphonse Lecampion, Seyyedmaalek Momeni, Christophe Nussbaum

Acoustic emission (AE) monitoring is commonly used to inspect the health of a structure continuously. During fracture processes elastic waves of AE are created and emitted, and sensors can capture these waves. The acquired signals can be processed to track ...

2023

Public-Key Encryption with Quantum Keys

Khashayar Barooti

In the framework of Impagliazzo's five worlds, a distinction is often made between two worlds, one where public-key encryption exists (Cryptomania), and one in which only one-way functions exist (MiniCrypt). However, the boundaries between these worlds can ...

Springer International Publishing Ag2023

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NATURE PORTFOLIO2023

Security in the Presence of Quantum Adversaries

Khashayar Barooti

EPFL2023

Multiomic analysis of HER2-enriched and AR-positive breast carcinoma with apocrine differentiation and an oligometastatic course: a case report

Andrea Cavalli

FRONTIERS MEDIA SA2023