Micromachined impedance spectroscopy flow cytometer for cell analysis and particle sizing
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The impedance of biological material changes with frequency, a phenomenon that has been discovered more than 100 years ago. It is due to the fact that the cell membrane acts as a capacitor which filters out currents at low frequency and lets them pass at h ...
Particle manifold method (PMM) is a new extension of the numerical manifold method (NMM). PMM uses a mathematical cover system to describe the motion and deformation of a particle-based physical domain. By introducing the concept of particle into NMM, PMM ...
In this letter, we propose a formula for evaluating the transfer impedance of two-layer braided cable shields. The proposed formula results from the combination of the model proposed by Vance for the evaluation of the equivalent transfer impedance of a two ...
Counting cells in a large microchannel remains challenging and is particularly critical for in vitro assays, such as cell adhesion assays. This paper addresses this issue, by presenting the development of interdigitated three-dimensional electrodes, which ...
A cross-coupled current mirror topology is presented. This topology increases the gain of a circuit that amplifies a pair of differential currents without increasing its power dissipation. An example circuit employing this current mirroring technique is pr ...
Since stem cells have the unique ability to produce more of themselves (i.e. to "self-renew") and to generate specialized tissue cells, they are an ideal source of cells for regenerative medicine and in vitro tissue models. In order to fully exploit this p ...
It is important to consider the microstructure of a material when studying the macroscopic mechanical properties. Although special equipments have been used for micromechanics study through experimental tests, it is limited by instruments and reproducibili ...
We report a reliable strategy to perform automated image cytometry of single (non-adherent) stem cells captured in microfluidic traps. The method rapidly segments images of an entire microfluidic chip based on the detection of horizontal edges of microflui ...
Integrated circuit Hall sensor system comprising a plurality of elementary blocks (EB), each elementary block including a Hall cell (4), a differential pair (8) of an input stage of a Differential Difference Amplifier (DDA), and terminals (12a, 12b), where ...
In the recent years, the development of automated systems for cellular monitoring has been highly promoted in basic biological research as well as in industries and medical diagnostic. Several methods for transduction of cellular signals have been investig ...