Publication
Asymmetric synthesis of polycyclic polyketides via the double Diels-Alder addition of 2,2 '-ethylidenebis[3,5-dimethylfuran]
Publications associées (40)
Catalytic Enantioselective Synthesis of Inherently Chiral Macrocycles by Dynamic Kinetic Resolution
Kinetically fast racemization of chiral substrates through an achiral intermediate and enantioselective functionalization of one of the enantiomeric substrates forms the basis of the dynamic kinetic resolution (DKR) of centrally chiral molecules. We report ...
2024Organocatalytic Enantioselective Pictet–Spengler Reaction of α‐Ketoesters: Development and Application to the Total Synthesis of (+)‐Alstratine A
Qian Wang, Jieping Zhu, Rémi Julien Sylvain Andres, Fenggang Sun
We report herein an asymmetric Pictet– Spengler reaction of α-ketoesters. In the presence of a catalytic amount of simple alanine-derived squaramide and p-nitrobenzoic acid, reaction of tryptamines with methyl 2-oxoalkanoates afforded the corresponding 1- ...
2023A general and robust Ni-based nanocatalyst for selective hydrogenation reactions at low temperature and pressure
Paul Joseph Dyson, Mingyang Liu, Yelin Hu, Matthias Beller
Catalytic hydrogenations are important and widely applied processes for the reduction of organic compounds both in academic laboratories and in industry. To perform these reactions in sustainable and practical manner, the development and applicability of n ...
Washington2023Taming the radical cation intermediate enabled one-step access to structurally diverse lignans
Jieping Zhu, Cédric Fung, Qiang Wang, Jia-Chen Xiang
Lignans, in spite of their structural diversity, are all biosynthetically derived from coniferyl alcohol. We report herein a divergent synthesis of lignans from biomass-derived monolignols in a short synthetic sequence. Blue LED irradiation of a dichlorome ...
2022Apparent 6-endo-trig Carbofluorination of Alkenes Enabled by Palladium-Based Dyotropic Rearrangement
Qian Wang, Jieping Zhu, Jing Gong
Alkene difunctionalization featuring an intramolecular carbometallation step has been developed into a powerful transformation in organic synthesis. The 5-exo-trig carbometallation is in general highly favored over the alternative 6-endo-trig cyclization. ...
WILEY-V C H VERLAG GMBH2022Construction of Functional Superhydrophobic Biochars as Hydrogen Transfer Catalysts for Dehydrogenation of N-Heterocycles
To endow metal-free materials with the high catalytic activity that is typically featured by a metal-based catalyst is yet a constant pursuit in the field of catalytic chemistry. In this work, novel functional biochars (DCNs) were prepared from wheat straw ...
AMER CHEMICAL SOC2021Catalytic Enantioselective Aminopalladation–Heck Cascade
Qian Wang, Jieping Zhu, Hua Wu, Yuping He, Jian Cao
Domino processes initiated by intramolecular nucleopalladation of alkynes have been developed into powerful synthetic tools for the synthesis of functionalized heterocycles. However, a catalytic enantioselective version of this class of reactions remains s ...
2021Carboxymethyl cellulose nanocomposite beads as super-efficient catalyst for the reduction of organic and inorganic pollutants
Carboxymethyl cellulose/copper oxide-nickel oxide (CMC/CuO-NiO) nanocomposite beads were prepared by facile, simple and environmentally friendlymethod. Initially, CuO-NiOwas prepared and applied for the catalytic reduction of 4-nitrophenol (4-NP). The resu ...
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