An asymmetric synthesis of the 3,5-dihydroxycyclohexanone subunit of baconipyrones A and B, as well as that of the hydroxydiketone subunit of baconipyrones C and D ((-)-(4S,6S)-4,6-dimethyl-5-hydroxynonan-3,7-dione), is described. Key steps include sulfur dioxide-induced additions of enoxysilanes to 1,3-dioxy-1,3-dienes, followed by retro-ene desulfitations (retro-ene elimination of SO2).
Bruno Emanuel Ferreira De Sousa Correia, Karla Montserrat Castro Gilabert, Basile Isidore Martin Wicky, Jue Wang
Henning Paul-Julius Stahlberg, Jasenko Zivanov
Bruno Emanuel Ferreira De Sousa Correia, Casper Alexander Goverde