In Vivo Testing of a Novel Adjustable Glaucoma Drainage Device

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Results of CO2 Laser-assisted Deep Sclerectomy as Compared With Conventional Deep Sclerectomy

André Mermoud, Sylvain Roy

Purpose: To evaluate the efficacy of CO2 laser-assisted sclerectomy surgery (CLASS) compared with classic nonpenetrating deep sclerectomy (NPDS) with implant in medically uncontrolled glaucoma patients. Materials and Methods: Patients who underwent primary ...

Lippincott, Williams & Wilkins2016

Engineered acellular collagen scaffold for endogenous cell guidance, a novel approach in urethral regeneration

Jeffrey Alan Hubbell, Peter Frey, Hans Mattias Larsson, Elif Vardar, Kalitha Pinnagoda, Ganesh Vythilingam

The treatment of congenital malformations or injuries of the urethra using existing autologous tissues can be associated with post-operative complications. Using rat-tail collagen, we have engineered an acellular high-density collagen tube. These tubes wer ...

Elsevier Sci Ltd2016

Cascaded PID controller for anaesthesia delivery

Monia Guidi, Alena Simalatsar

The technologies for continuous measurement of the anaesthetic agents circulating in body fluids are not mature yet, though some preliminary prototypes exist already. We present a control algorithm that based on the real measurement of propofol plasma conc ...

2016

Contribution of the Arterial System and the Heart to Blood Pressure during Normal Aging - A Simulation Study

Nikolaos Stergiopoulos, Elira Maksuti, Nico Westerhof

During aging, systolic blood pressure continuously increases over time, whereas diastolic pressure first increases and then slightly decreases after middle age. These pressure changes are usually explained by changes of the arterial system alone (increase ...

Public Library of Science2016

Implant-based three-dimensional superimposition of the growing mandible in a rabbit model

The reliable assessment of craniofacial morphological changes during growth requires invariant regions for image registration. As these regions have not yet been identified in three dimensions, intra-osseous implants are required as fiducial markers for th ...

Oxford Univ Press2016

Optical properties of rabbit brain in the red and near-infrared: changes observed under in vivo, postmortem, frozen, and formalin-fixated conditions

Georges Wagnières, Matthieu Philippe Emmanuel Zellweger, Blaise Lovisa, Andreas Pitzschke

The outcome of light-based therapeutic approaches depends on light propagation in biological tissues, which is governed by their optical properties. The objective of this study was to quantify optical properties of brain tissue in vivo and postmortem and a ...

SPIE Society of Photo-optical Instrumentation Engineers2015

A New Noninvasively Adjustable Glaucoma Drainage Device

Adan Villamarin

Glaucoma is an irreversible disease affecting the eye, leading to progressive loss of vision and eventually to total blindness. It is often related to high intraocular pressure (IOP), which results from increased outflow resistance to aqueous humor. The fi ...

EPFL2014

A New Adjustable Glaucoma Drainage Device

Nikolaos Stergiopoulos, Sylvain Roy, Adan Villamarin, Stéphane Bigler

PURPOSE. This work is focused on the testing of a new experimental noninvasively adjustable glaucoma drainage device (AGDD) that allows for the control of its outflow resistance to modulate intraocular pressure (IOP) in a customized fashion. METHODS. Six A ...

Association for Research in Vision and Ophthalmology2014

First in vivo application and evaluation of a novel method for non-invasive estimation of cardiac output

Nikolaos Stergiopoulos, Orestis Vardoulis

Surgical or critically ill patients often require continuous assessment of cardiac output (CO) for diagnostic purposes or for guiding therapeutic interventions. A new method of non-invasive CO estimation has been recently developed, which is based on press ...

Elsevier2014

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Optical properties of rabbit brain in the red and near-infrared: changes observed under in vivo, postmortem, frozen, and formalin-fixated conditions

Georges Wagnières, Matthieu Philippe Emmanuel Zellweger, Blaise Lovisa, Andreas Pitzschke

SPIE Society of Photo-optical Instrumentation Engineers2015