Publications associées à A Multifunctional Lipoxygenase with Fatty Acid Hydroperoxide Cleaving Activity from the Moss Physcomitrella patens

The DEAD-box RNA helicase CshA is required for fatty acid homeostasis inStaphylococcus aureus

Staphylococcus aureusis an opportunistic pathogen that can grow in a wide array of conditions: on abiotic surfaces, on the skin, in the nose, in planktonic or biofilm forms and can cause many type of infections. Consequently,S.aureusmust be able to adapt r ...

PUBLIC LIBRARY SCIENCE2020

Chapter 6: Production and Applications of Polyunsaturated Fatty Acids

Edgard Gnansounou, Binod Parameswaran, Ummalyma Sabeela Beevi

Polyunsaturated fatty acids (PUFAs) are key molecules for the control of human as well as animal health. Among the PUFAs, docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) are vital compounds for infant brain development and other immune regulator ...

Wiley2019

Structural basis for regulation of human acetyl-CoA carboxylase

Henning Paul-Julius Stahlberg, Yakir Guri

Acetyl-CoA carboxylase catalyses the ATP-dependent carboxylation of acetyl-CoA, a rate-limiting step in fatty acid biosynthesis(1,2). Eukaryotic acetyl-CoA carboxylases are large, homodimeric multienzymes. Human acetyl-CoA carboxylase occurs in two isoform ...

Springer Nature2018

Dysregulation of soluble epoxide hydrolase and lipidomic profiles in anorexia nervosa

Pierre Magistretti, Jiangyan Yang

Individuals with anorexia nervosa (AN) restrict eating and become emaciated. They tend to have an aversion to foods rich in fat. Because epoxide hydrolase 2 (EPHX2) was identified as a novel AN susceptibility gene, and because its protein product, soluble ...

Nature Publishing Group2016

Measuring changes in substrate utilization in the myocardium in response to fasting using hyperpolarized [1-(13)C]butyrate and [1-(13)C]pyruvate

Arnaud Comment, Josefina Adriana Maria Bastiaansen

Cardiac dysfunction is often associated with a shift in substrate preference for ATP production. Hyperpolarized (HP) (13)C magnetic resonance spectroscopy (MRS) has the unique ability to detect real-time metabolic changes in vivo due to its high sensitivit ...

2016

A rheostat mechanism governs the bifurcation of carbon flux in mycobacteria

Matteo Dal Peraro, John McKinney, Florence Pojer, Giulia Fonti, Paul Murima, Tarun Chopra

Fatty acid metabolism is an important feature of the pathogenicity of Mycobacterium tuberculosis during infection. Consumption of fatty acids requires regulation of carbon flux bifurcation between the oxidative TCA cycle and the glyoxylate shunt. In Escher ...

Nature Publishing Group2016

Keys to Lipid Selection in Fatty Acid Amide Hydrolase Catalysis: Structural Flexibility, Gating Residues and Multiple Binding Pockets

Ursula Röthlisberger, Andrea Cavalli, Pablo Campomanes Ramos, Giulia Palermo

The fatty acid amide hydrolase (FAAH) regulates the endocannabinoid system cleaving primarily the lipid messenger anandamide. FAAH has been well characterized over the years and, importantly, it represents a promising drug target to treat several diseases, ...

2015

Quantitative Mass Spectrometry Reveals Plasticity of Metabolic Networks in Mycobacterium smegmatis

John McKinney, Romain Hamelin, Florence Armand, Diego Chiappe, Marc Moniatte, Tarun Chopra

Mycobacterium tuberculosis has a remarkable ability to persist within the human host as a clinically inapparent or chronically active infection. Fatty acids are thought to be an important carbon source used by the bacteria during long term infection. Catab ...

Amer Soc Biochemistry Molecular Biology Inc2014

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A Multifunctional Lipoxygenase with Fatty Acid Hydroperoxide Cleaving Activity from the Moss Physcomitrella patens

Preferential retention of algal carbon in benthic invertebrates: Stable isotope and fatty acid evidence from an outdoor flume experiment

The DEAD-box RNA helicase CshA is required for fatty acid homeostasis inStaphylococcus aureus

Chapter 6: Production and Applications of Polyunsaturated Fatty Acids

Structural basis for regulation of human acetyl-CoA carboxylase

Development of an albumin-binding ligand for prolonging the plasma half-life of peptide therapeutics

Dysregulation of soluble epoxide hydrolase and lipidomic profiles in anorexia nervosa

Measuring changes in substrate utilization in the myocardium in response to fasting using hyperpolarized [1-(13)C]butyrate and [1-(13)C]pyruvate

A rheostat mechanism governs the bifurcation of carbon flux in mycobacteria

Keys to Lipid Selection in Fatty Acid Amide Hydrolase Catalysis: Structural Flexibility, Gating Residues and Multiple Binding Pockets

Quantitative Mass Spectrometry Reveals Plasticity of Metabolic Networks in Mycobacterium smegmatis

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Chattez avec Graph Search

Preferential retention of algal carbon in benthic invertebrates: Stable isotope and fatty acid evidence from an outdoor flume experiment

Dysregulation of soluble epoxide hydrolase and lipidomic profiles in anorexia nervosa

Structural basis for regulation of human acetyl-CoA carboxylase

Measuring changes in substrate utilization in the myocardium in response to fasting using hyperpolarized [1-(13)C]butyrate and [1-(13)C]pyruvate

A rheostat mechanism governs the bifurcation of carbon flux in mycobacteria

Quantitative Mass Spectrometry Reveals Plasticity of Metabolic Networks in Mycobacterium smegmatis

The DEAD-box RNA helicase CshA is required for fatty acid homeostasis inStaphylococcus aureus

Chapter 6: Production and Applications of Polyunsaturated Fatty Acids

Development of an albumin-binding ligand for prolonging the plasma half-life of peptide therapeutics

Keys to Lipid Selection in Fatty Acid Amide Hydrolase Catalysis: Structural Flexibility, Gating Residues and Multiple Binding Pockets