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Factors affecting the production and quality of IgA antibodies active against V. cholerae

Publications associées (33)

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Glycodendrimers, such as glycoclusters and glycopolymers, are known to be very useful molecules to probe carbohydrate-lectin interactions. Herein, new second generation glycopeptide dendrimers (G2a-f) presenting a L-lysin-based (Lys) tetraantennary scaffol ...

Royal Society of Chemistry2011

During the past decades the field of sensors has been subject to much attention due to an increased demand for (bio)sensors and environmental monitoring. The efforts have been concentrated to create sensors which are reliable, highly sensitive and selectiv ...

EPFL2011

Electron Capture Dissociation Product Ion Abundances at the X Amino Acid in RAAAA-X-AAAAK Peptides Correlate with Amino Acid Polarity and Radical Stability

Yury Tsybin, Hisham Ben Hamidane, Aleksey Vorobyev

We present mechanistic studies aimed at improving the understanding of the product ion formation rules in electron capture dissociation (ECD) of peptides and proteins in Fourier transform ion cyclotron resonance mass spectrometry. In particular, we attempt ...

Springer-Verlag2009

Synthesis, structural characterization and applications of hyperbranched polymers based on L-lysine

Markus Scholl

L-lysine is an essential a-amino acid and a necessary building block for all proteins in the body. As an essential amino acid, L-lysine is not synthesized by humans or animals. Industrially produced L-lysine has therefore a big market as food additive, e.g ...

EPFL2007

Inferring thermodynamic properties from CCN activation experiments: Single-component and binary aerosols

Athanasios Nenes

This study presents a new method, Köhler Theory Analysis (KTA), to infer the molar volume and solubility of organic aerosol constituents. The method is based on measurements of surface tension, chemical composition, and CCN activity coupled with Köhler the ...

European Geosciences Union2007

Metal-based chemosensors for amino acids, peptides, and nucleotides

Andrey Buryak

An organometallic 4d transition metal complex [CpRhCl2]2, together with commercially available dyes, was used to construct indicator displacement assays (IDAs) for the detection of peptides, amino acids, and nucleotides. The combination of the CpRh compl ...

EPFL2007

An amino or thiol linker building block for the synthesis of amino or thiol functionalized amino acids and generally of the following structure: Formula XII is provided. Such building block may be introduced in the 5' end position of an amino acid under st ...

2006

Mutants of o6-alkylguanine-dna alkyltransferase

Kai Johnsson, Christian Heinis, Alexandre Juillerat, Christopher Chidley, Thomas Gronemeyer, Antje Keppler

The invention relates to AGT mutants showing, when compared to the wild type human AGT, two or more advantageous properties selected from (a) reduced DNA interaction (b) localisation of the expressed protein in eukaryotic cells that is no longer restricted ...

2006

RNA-sequence or nucleoside/nucleotide analogues and method for producing the analogues

Sébastien Porcher

Nucleic acid sequence analogues, in particular tRNA analogues comprising in the place of a 3'-terminal adenosine a 3'-terminal 2'-deoxy-2'-thioadenosine are able to react site-specifically with weakly activated amino acid derivatives (e.g. phenylthioesters ...

2006

Importance of the structure of vancomycin binding pocket in designing compounds active against vancomycin-resistant enterococci (VRE)

Jieping Zhu

16-Membered meta,para-cyclophanes mimicking the vancomycin binding pocket (D-O-E ring) are designed and synthesized. The structural features of these biaryl ether contg. macrocycles are: (a) the deletion of the carboxyl group of vancomycin's central amino ...

2006