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(ω-1)-Fluoroalk-(ω-1)-enoic Acids: Potential Fungicides

Publications associées (33)

Molecular analysis and therapeutic applications of human serum albumin-fatty acid interactions

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Human serum albumin (hSA) is the major carrier protein for fatty acids (FAs) in plasma. Its ability to bind multiple FA moieties with moderate to high affinity has inspired the use of FA conjugation as a safe and natural platform to generate long-lasting t ...

ELSEVIER2022

Functional and Computational Genomics Reveal Unprecedented Flexibility in Stage-Specific Toxoplasma Metabolism

Vassily Hatzimanikatis, Matteo Lunghi, Damien Lionel Nicolas, Anush Chiappino-Pepe, Aarti Krishnan, Dominique Soldati-Favre

To survive and proliferate in diverse host environments with varying nutrient availability, the obligate intracellular parasite Toxoplasma gondii reprograms its metabolism. We have generated and curated a genome-scale metabolic model (iTgo) for the fast-re ...

CELL PRESS2020

The DEAD-box RNA helicase CshA is required for fatty acid homeostasis inStaphylococcus aureus

Bianca Marie Petrignani

Staphylococcus aureusis an opportunistic pathogen that can grow in a wide array of conditions: on abiotic surfaces, on the skin, in the nose, in planktonic or biofilm forms and can cause many type of infections. Consequently,S.aureusmust be able to adapt r ...

PUBLIC LIBRARY SCIENCE2020

Hemagglutinin of Influenza A, but not of Influenza B and C viruses is acylated by ZDHHC2, 8, 15 and 20

Françoise Gisou van der Goot Grunberg, Laurence Gouzi Abrami, Mohamed Adbelalim Gadalla

Hemagglutinin (HA), a glycoprotein of Influenza A viruses and its proton channel M2 are site-specifically modified with fatty acids. Whereas two cysteines in the short cytoplasmic tail of HA contain only palmitate, stearate is exclusively attached to one c ...

PORTLAND PRESS LTD2020

Novel Molecular Probes for Non-invasive Optical Imaging of Fatty Acid and Triglyceride Uptake in Living Animals

Grigory Karateev

Molecular imaging allows noninvasive visualization of biological processes in their native environment within living systems. It can give a better understanding of fundamental biology, help in identifying disease mechanisms and visualizing pathological tis ...

EPFL2019

A cellulolytic fungal biofilm enhances the consolidated bioconversion of cellulose to short chain fatty acids by the rumen microbiome

Robert Lawrence Shahab

The ability of the multispecies biofilm membrane reactors (MBM reactors) to provide distinguished niches for aerobic and anaerobic microbes at the same time was used for the investigation of the consolidated bioprocessing of cellulose to short chain fatty ...

2019

Chapter 6: Production and Applications of Polyunsaturated Fatty Acids

Edgard Gnansounou, Binod Parameswaran, Ummalyma Sabeela Beevi

Polyunsaturated fatty acids (PUFAs) are key molecules for the control of human as well as animal health. Among the PUFAs, docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) are vital compounds for infant brain development and other immune regulator ...

Wiley2019

Sterol regulatory element binding protein 1 couples mechanical cues and lipid metabolism

Giovanni Sorrentino

Sterol regulatory element binding proteins (SREBPs) are a family of transcription factors that regulate lipid biosynthesis and adipogenesis by controlling the expression of several enzymes required for cholesterol, fatty acid, triacylglycerol and phospholi ...

Springer2019

Modeling CLiMP-63 spatio-temporal distribution and its interplay with Post-translational modification

Laurence Gouzi Abrami, Béatrice Kunz, Sylvia Ho, Patrick Alain Sandoz, Robin Alexander Denhardt-Eriksson

Post-translational modifications may affect a protein’s localization, half-life or structural conformation. Palmitoylation is the only re- versible lipid modification known to date. It involves the attachment of a fatty acid (palmitoyl) to a protein. Here, ...

2018

Measuring changes in substrate utilization in the myocardium in response to fasting using hyperpolarized [1-(13)C]butyrate and [1-(13)C]pyruvate

Arnaud Comment, Josefina Adriana Maria Bastiaansen

Cardiac dysfunction is often associated with a shift in substrate preference for ATP production. Hyperpolarized (HP) (13)C magnetic resonance spectroscopy (MRS) has the unique ability to detect real-time metabolic changes in vivo due to its high sensitivit ...

2016

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