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At early age, ultra high performance fibre reinforced concretes (UHPFRC)undergo significant volumes changes (thermal deformation and autogenous shrinkage)related to their composition. These deformations can be restrained by different elements respective to ...
A simple three-step procedure converted the readily accessible (2-bromo-1,1-difluoroethyl)arenes into a-aryl-a,a-difluoroacetaldehydes. Subsequent hydrocyanation, hydrolysis, oxidn. and again hydrolysis afforded b-aryl-b,b-difluoro-a-oxopropionic acids. Re ...
This paper discusses separable term structure diffusion models in an arbitrage-free environment. Using general consistency results we exploit the interplay between the diffusion coefficients and the functions determining the forward curve. We introduce the ...
Structure and dynamics of substrate binding (cefotaxime) to the catalytic pocket of the mononuclear zinc-beta-lactamase from Bacillus cereus are investigated by molecular dynamics simulations. The calculations, which are based on the hydrogen-bond pattern ...
A phospho-directed nanoreactor with multiple functions is reported. Alumina-functionalized macroporous ordered silica foams (Al-MOSF) have been developed with large pore size, high pore volume (1.6 cm(3)/g), and a surface area of 186 m(2)/g rich in coordin ...
Prediction error identification requires that data be informative with respect to the chosen model structure. Whereas sufficient conditions for informative experiments have been available for a long time, there were surprisingly no results of necessary and ...
The activity of penicillin acylase has been studied in aq. and org. solvents, as free enzyme as well as immobilized within the membrane of liq.-core capsules. The activity of the enzyme is inhibited by the accumulation of the products of the hydrolysis rea ...
A novel type of water-soluble prodrugs of cyclosporine A (CsA) is described, featuring a modular system of an enzyme-cleavable group, a solubilizing moiety and a chemodegradable spacer attached to the hydroxyl function of (4R)-4-[(E)-2-butenyl]-4-,N-dimeth ...
A method for labeling acyl carrier protein (ACP) fusion proteins using derivs. of CoA is described. The method relies on the transfer of a label from a CoA type substrate to an ACP fusion protein using a holo-acyl carrier protein synthase (ACPS) or a homol ...
(EPFL-Ecole Polytechnique Federale de Lausanne, Switz.).2004
A central debate regarding neocortical function concerns the degree to which the underlying microcircuitry is stereotypically organized. Stereotypy reflects invariance in structure and function, as a result of common genetic templates and environmental con ...
