Publication
Plasticity of transposed rhombomeres: Hox gene induction is correlated with phenotypic modifications
Publications associées (55)
Circletail, a new mouse mutant with severe neural tube defects: chromosomal localization and interaction with the loop-tail mutation
Circletail (Crc) is a new mouse mutant that exhibits a severe form of neural tube defect, craniorachischisis, in which almost the entire neural tube fails to close. This phenotype is seen in very few other mutants, the best characterized of which is loop-t ...
2001Retinal axon misrouting at the optic chiasm in mice with neural tube closure defects
In a new mouse mutant, circletail (Crc), failure of neural tube closure (embryonic day [E] 8-9) is associated with errors in retinal axon projection at the optic chiasm (E12-18), such that many axons normally projecting contralaterally instead grow to ipsi ...
2000Patterning signals acting in the spinal cord override the organizing activity of the isthmus
The regionalization of the neural tube along the anteroposterior axis is established through the action of patterning signals from the endo-mesoderm including the organizer. These signals set up a pre-pattern which is subsequently refined through local pat ...
1999Defined concentrations of a posteriorizing signal are critical for MafB/Kreisler segmental expression in the hindbrain
It has been shown by using the quail/chick chimera system that Hox gene expression in the hindbrain is influenced by positional signals arising from the environment. In order to decipher the pathway that leads to Hox gene induction, we have investigated wh ...
1998Determination of the identity of the derivatives of the cephalic neural crest: incompatibility between Hox gene expression and lower jaw development
In addition to pigment cells, and neural and endocrine derivatives, the neural crest is characterized by its ability to yield mesenchymal cells. In amniotes, this property is restricted to the cephalic region from the mid-diencephalon to the end of rhombom ...
1998The expression patterns of endothelin-A receptor and endothelin 1 in the avian embryo
We investigated the expression pattern of the endothelin-A receptor and endothelin 1 genes, the mutations of which affect the development of the mesectodermal derivatives of the neural crest. We show here that endothelin 1 is expressed by the environment o ...
1998The avian fli gene is specifically expressed during embryogenesis in a subset of neural crest cells giving rise to mesenchyme
The ets-family of transcription factors is involved in the development of endothelial and hematopoietic cells. Among these genes, fli was shown to be responsible for erythroblastomas and Ewing's sarcomas. Its involvement in Ewing's sarcoma, a putative neur ...
1998Failure of ventral closure and axial rotation in embryos lacking the proprotein convertase Furin
We have examined the role of Furin in postimplantation-stage mouse embryos by analyzing both the expression pattern of fur mRNA and the developmental consequences of a loss-of-function mutation at the fur locus. At early stages (day 7.5), fur mRNA is abund ...
1998Hox gene induction in the neural tube depends on three parameters: competence, signal supply and paralogue group
It has been previously shown that Hox gene expression in the rhombencephalon is controlled by environmental cues. Thus posterior transposition of anterior rhombomeres to the r7/8 level results in the activation of Hox genes of the four first paralog groups ...
1997[Genetic control of rhombencephalon development by Hox genes studied in bird embryo by the quail-chick chimera method]
The rhombencephalic neural tube is transiently segmented along the anteroposterior axis into 8 rhombomeres. Each rhombomere, as well as its derived neural crest cells, is characterized by the expression of a specific set of Hox genes which constitute its H ...
1997