Photoprotective effect of catechin during ALA-PDT

The production of reactive oxygen species (ROS) in normal tissues is associated with side effects of many cancer treatments. This is, in particular, the case for the skin photosensitization experienced by certain patients subjected to PDT based on a systemic administration of photosensitizers (PS). Similarly, the ROS generated in normal tissues during radiotherapies are responsible for the damages induced in various organs, including the skin.