Publication

Rescue of secretion of rare-disease-associated misfolded mutant glycoproteins in UGGT1 knock-out mammalian cells

Publications associées (31)

Homogenization theory captures macroscopic flow discontinuities across Janus membranes

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Janus membranes, thin permeable structures with chemical and geometrical asymmetric properties, show great potential in industrial separation processes. Yet the link between the micro- and macro-scale behaviours of these membranes needs to be established r ...

Cambridge University Press2023

Structural diversity of photoswitchable sphingolipids for optodynamic control of lipid microdomains

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Sphingolipids are a structurally diverse class of lipids predominantly found in the plasma membrane of eukaryotic cells. These lipids can laterally segregate with other rigid lipids and cholesterol into liquid-ordered domains that act as organizing centers ...

2023

Effects of thermal, mechanical, and electrostatic perturbations on lipid membrane hydration investigated by second harmonic imaging

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Hydrated lipid bilayer membranes are crucial components of cells and organelles, serving as the outer boundary that separates the cellular components from the extracellular environment. Lipid membranes regulate their structures and functions by dynamically ...

EPFL2023

Micro- or nanostructured optical element

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A micro- or nanostructured optical element (1) is proposed comprising: a membrane (3) with an array of holes (5), the membrane (3) comprising a membrane light wave facing surface; an array of pillars (7) sized and shaped such that a respective pillar (7) i ...

2023

High throughput wide field second harmonic imaging of giant unilamellar vesicles

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Cell-sized giant unilamellar vesicles (GUVs) are an ideal tool for understanding lipid membrane structure and properties. Label-free spatiotemporal images of their membrane potential and structure would greatly aid the quantitative understanding of membran ...

AIP Publishing2023

Mechanical Properties and Nanomotion of BT-20 and ZR-75 Breast Cancer Cells Studied by Atomic Force Microscopy and Optical Nanomotion Detection Method

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Cells of two molecular genetic types of breast cancer-hormone-dependent breast cancer (ZR-75 cell line) and triple-negative breast cancer (BT-20 cell line)-were studied using atomic force microscopy and an optical nanomotion detection method. Using the Pea ...

MDPI2023

Simultaneous Electrophysiology and Imaging Reveal Changes in Lipid Membrane Thickness and Tension upon Uptake of Amphiphilic Gold Nanoparticles

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Amphiphilic gold core nanoparticles (AmNPs) striped with hydrophilic 11-mercapto-1-undecanesulfonate (MUS) and hydrophobic 1-octanethiol (OT) ligands are promising candidates for drug carriers that passively and nondisruptively enter cells. Yet, how they i ...

Amer Chemical Soc2023

Multivalent Virucidal Antivirals: Synthesis, Mechanisms of Action, and Immune-stimulating Effects

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Viruses initiate invasion by binding to cell surface glycoproteins. Materials mimicking the carbohydrate motifs of these glycoproteins, such as heparan sulfate (HS) and sialic acid (SA) can block viral attachment and inhibit the infection. Multivalent disp ...

EPFL2023

Background Rejection in Two-Photon Fluorescence Image Scanning Microscopy

Giorgio Tortarolo

We discuss the properties of signal strength and integrated intensity in two-photon excitation confocal microscopy and image scanning microscopy. The resolution, optical sectioning and background rejection are all improved over nonconfocal two-photon micro ...

MDPI2023

Rescue of secretion of rare-disease-associated misfolded mutant glycoproteins in UGGT1 knock-out mammalian cells

Homogenization theory captures macroscopic flow discontinuities across Janus membranes

Structural diversity of photoswitchable sphingolipids for optodynamic control of lipid microdomains

Effects of thermal, mechanical, and electrostatic perturbations on lipid membrane hydration investigated by second harmonic imaging

Micro- or nanostructured optical element

High throughput wide field second harmonic imaging of giant unilamellar vesicles

Mechanical Properties and Nanomotion of BT-20 and ZR-75 Breast Cancer Cells Studied by Atomic Force Microscopy and Optical Nanomotion Detection Method

Simultaneous Electrophysiology and Imaging Reveal Changes in Lipid Membrane Thickness and Tension upon Uptake of Amphiphilic Gold Nanoparticles

Multivalent Virucidal Antivirals: Synthesis, Mechanisms of Action, and Immune-stimulating Effects

Background Rejection in Two-Photon Fluorescence Image Scanning Microscopy

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Homogenization theory captures macroscopic flow discontinuities across Janus membranes

Structural diversity of photoswitchable sphingolipids for optodynamic control of lipid microdomains

Effects of thermal, mechanical, and electrostatic perturbations on lipid membrane hydration investigated by second harmonic imaging

Micro- or nanostructured optical element

High throughput wide field second harmonic imaging of giant unilamellar vesicles

Mechanical Properties and Nanomotion of BT-20 and ZR-75 Breast Cancer Cells Studied by Atomic Force Microscopy and Optical Nanomotion Detection Method

Simultaneous Electrophysiology and Imaging Reveal Changes in Lipid Membrane Thickness and Tension upon Uptake of Amphiphilic Gold Nanoparticles

Multivalent Virucidal Antivirals: Synthesis, Mechanisms of Action, and Immune-stimulating Effects

Rheological Properties of Ionically Crosslinked Viscoelastic 2D Films vs. Corresponding 3D Bulk Hydrogels

Background Rejection in Two-Photon Fluorescence Image Scanning Microscopy

Rheological Properties of Ionically Crosslinked Viscoelastic 2D Films vs. Corresponding 3D Bulk Hydrogels