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IR-induced conformational isomerization of a helical peptide in a cold ion trap

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Amplitude and phase reconstruction for Low-Energy Electron Holography of individual proteins

Hannah Julia Ochner

Single-molecule imaging methods are of importance in structural biology, and specifically in the imaging of proteins, since they can elucidate conformational variability and structural changes that might be lost in imaging methods relying on averaging proc ...

EPFL2022

NIR Fluorescence lifetime macroscopic imaging with a time-gated SPAD camera

Edoardo Charbon, Claudio Bruschini, Arin Can Ülkü

The performance of SwissSPAD2 (SS2), a large scale, widefield time-gated CMOS SPAD imager developed for fluorescence lifetime imaging, has recently been described in the context of visible range and fluorescence lifetime imaging microscopy (FLIM) of dyes w ...

SPIE-INT SOC OPTICAL ENGINEERING2022

High-useful yield and new autoionizing state of resonantly ionized tungsten

Reto Georg Trappitsch

In order to measure tungsten isotopic composition in presolar stardust grains that contain a limited number of atoms, we developed a new three-photon three-color resonance ionization scheme using titanium:sapphire lasers and the Laser Ionization of Neutral ...

ROYAL SOC CHEMISTRY2022

Visualization, Interactive Handling and Simulation of Molecules in Commodity Augmented Reality in Web Browsers Using moleculARweb's Virtual Modeling Kits

Matteo Dal Peraro, Luciano Andres Abriata, Fabio Jose Cortes Rodriguez, Lucien Fabrice Krapp

moleculARweb (https://molecularweb.epfl.ch) began as a website for education and outreach in chemistry and structural biology through augmented reality (AR) content that runs in the web browsers of regular devices like smartphones, tablets, and computers. ...

SWISS CHEMICAL SOC2022

Tailored deformation behavior of 304L stainless steel through control of the crystallographic texture with laser-powder bed fusion

Roland Logé, Christian Leinenbach, Markus Strobl, Efthymios Polatidis

Laser-powder bed fusion (L-PBF) has gained significant research interest, not only for its profound advantage of producing near-net shape complex geometries of metallic parts, but also for the possibility of producing tailored microstructures. Here we expl ...

ELSEVIER SCI LTD2022

Sensitivity and spectral control of network lasers

Alexis Arnaudon, Dinika Saxena

Recently, random lasing in complex networks has shown efficient lasing over more than 50 localised modes, promoted by multiple scattering over the underlying graph. If controlled, these network lasers can lead to fast-switching multifunctional light source ...

Nature Portfolio2022

Platicon microcomb generation using laser self-injection locking

Tobias Kippenberg, Rui Ning Wang, Junqiu Liu, Wenle Weng, Jijun He, Yang Liu, Miles Henry Anderson

The past decade has witnessed major advances in the development and system-level applications of photonic integrated microcombs, that are coherent, broadband optical frequency combs with repetition rates in the millimeter-wave to terahertz domain. Most of ...

Nature Portfolio2022

Deep learning approaches for conformational flexibility and switching properties in protein design

Patrick Daniel Barth, Lucas Sebastian Powell-Rudden, Mahdi Hijazi

Following the hugely successful application of deep learning methods to protein structure prediction, an increasing number of design methods seek to leverage generative models to design proteins with improved functionality over native proteins or novel str ...

2022

Defect formation and mitigation during laser powder bed fusion of copper

Carl Tore Viktor Lindström

Additive manufacturing (AM) is a group of processing technologies which has the potential to revolutionize manufacturing by allowing easy manufacturing of complex shapes and small series. One AM-method which is of high interest for processing of metals is ...

EPFL2021

Is a Single Conformer Sufficient to Describe the Reorganization Energy of Amorphous Organic Transport Materials?

Anne-Clémence Corminboeuf, Iwona Swiderska, Kun-Han Lin, Raimon Fabregat I De Aguilar-Amat, Jacob Terence Blaskovits, Hélène Wu

The reorganization energy (lambda), which quantifies the structural rearrangement of a molecule when accommodating a charge, is a key parameter in the evaluation of charge mobility in molecular solids. However, it is unclear how lambda is influenced by con ...

AMER CHEMICAL SOC2021

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