Publications associées à Unraveling cartilage degeneration through synergistic effects of hydrostatic pressure and biomimetic temperature increase

Synergetic Support of Cartilage Homeostasis via Coupled Thermal-Hydrostatic Pressure Stimuli

Cartilage homeostasis, crucial for musculoskeletal function, is orchestrated by interconnected biophysical cues. In healthy cartilage, repetitive compressive loading not only elicits a range of mechanical stimuli but also induces a gradual transient temper ...

EPFL2024

Pressure-Induced Enlargement and Ionic Current Rectification in Symmetric Nanopores

Aleksandra Radenovic, Andrey Chernev, Sanjin Marion, Michal Daniel Macha, Sebastian James Davis

Nanopores in solid state membranes are a tool able to probe nanofluidic phenomena or can act as a single molecular sensor. They also have diverse applications in filtration, desalination, or osmotic power generation. Many of these applications involve chem ...

2020

Distributed hydrostatic pressure measurement using phase OTDR in a highly birefringent photonic crystal fiber

Luc Thévenaz, Li Zhang

Although distributed fiber-optic sensing of axial strain and temperature is a well-established technique, there are almost no demonstrations of distributed hydrostatic pressure sensing. The main obstacle for such measurements is the low sensitivity to pres ...

IEEE Institute of Electrical and Electronics Engineers2019

Effect of spilling from adjacent orifices on the velocity field and pressures in front of needle stop-logs

Giovanni De Cesare, Azin Amini, Cédric Bron, Ivan Stojnic

In this study, the effect of spilling from neighboring sluice gates on stop-logs was experimentally investigated on a 1:65 physical scale model comprised of a double arch dam, a reservoir area, six spillway orifices and two stop-logs. Two types of measurem ...

2018

Intrinsic viscoelasticity increases temperature in knee cartilage under physiological loading

Dominique Pioletti, Philippe Abdel Sayed, Mohamadreza Nassajian Moghadam

Metabolism of proteoglycans and hyaluronic acid has been shown to be temperature- dependent in cartilage explants, with optimal anabolic effects between 36 1C and 38 1C. At rest, the temperature of human knee has a value of around 33 1C. We aim to show in ...

Elsevier2014

The effect of pressure gradient on the collapse of cavitation bubbles in normal and reduced gravity

Marc Tinguely

When water flows through hydraulic turbomachines, the local pressure can become low enough to vaporize the water and create vapor cavities. This phenomenon is called cavitation. When the cavities collapse, shock waves and liquid jets traveling through the ...

EPFL2013

Response of an Embedded Block Impacted by High-Velocity Jets

Matteo Paolo Elia Antonio Federspiel

High-velocity plunging jets, issuing from ood release structures of dams, may result in scouring of the rocky riverbed and even endanger the foundation of the dams. Assessment of the scour extent is essential to ensure the safety of the dam and appurtenant ...

EPFL2011

Pattern-Based Sensing of Sulfated Glycosaminoglycans with a Dynamic Mixture of Iron Complexes

Kay Severin

A dynamic mixture of iron complexes was used as a colorimetric sensor for sulfated glycosaminoglycans. The sensing ensemble was prepared by mixing [FeCl2(H2O)4] with dipicolylamine, the functionalized bipyridyl ligand N-(6-aminohexyl)-4'-methyl-2,2'-bipyri ...

Royal Society of Chemistry2010

Continuous-wave far-infrared ESR spectrometer for high-pressure measurements

László Forró, Andrzej Sienkiewicz, Richard Gaal, Bálint Náfrádi

We present a newly-developed microwave probe for performing sensitive high-field/multi-frequency electron spin resonance (ESR) measurements under high hydrostatic pressures. The system consists of a BeCu-made pressure-resistant vessel, which accommodates t ...

Academic Press Inc - Elsevier Science2008