Publications associées à Modelled effects of prawn aquaculture on poverty alleviation and schistosomiasis control

Advancing first principle-based molecular dynamics of biological systems with machine learning

Molecular dynamics (MD) simulations have emerged as a transformative approach to analyse molecular systems at the atomic level, offering valuable insights into complex biological processes. Many biological phenomena can only accurately be described by inco ...

EPFL2023

Hookworms Evade Host Immunity by Secreting a Deoxyribonuclease to Degrade Neutrophil Extracellular Traps

Arne Seitz, Romain Guiet, Nicola Harris, Beatrice Volpe, Tiffany Babette Angélique Bouchery, Kathleen Shah, Mati André Marie Moyat, Manuel Kulagin

Hookworms cause a major neglected tropical disease, occurring after larvae penetrate the host skin. Neutrophils are phagocytes that kill large pathogens by releasing neutrophil extracellular traps (NETs), but whether they target hookworms during skin infec ...

CELL PRESS2020

Individual differences in the Müller-Lyer and Ponzo illusions are stable across different contexts

Michael Herzog, Aline Françoise Cretenoud, Lukasz Grzeczkowski

Vision scientists have attempted to classify visual illusions according to certain aspects, such as brightness or spatial features. For example, Piaget proposed that visual illusion magnitudes either decrease or increase with age. Subsequently, it was sugg ...

2020

Inference methods for the study of interacting biological oscillators in single-cells

Colas Noé Droin

Biological oscillators are pervasive in biology, covering all aspects of life from enzyme kinetics reactions to population dynamics. Although their behaviour has been intensively studied in the last decades, the recent advances of high-throughput experimen ...

EPFL2020

Gene drives for schistosomiasis transmission control

Francisco Javier Perez Saez

Schistosomiasis is one of the most important and widespread neglected tropical diseases (NTD), with over 200 million people infected in more than 70 countries; the disease has nearly 800 million people at risk in endemic areas. Although mass drug administr ...

2019

Space and time predictions of schistosomiasis snail host population dynamics across hydrologic regimes in Burkina Faso

Andrea Rinaldo, Theophile Mande, Francisco Javier Perez Saez

The ecology of the aquatic snails that serve as obligatory intermediate hosts of human schistosomiasis is driven by climatic and hydrological factors which result in specific spatial patterns of occurrence and abundance. These patterns in turn affect, join ...

2019

Sustainable Development, Planning and Poverty Alleviation

Jean-Claude Bolay, Eléonore Labattut

In 2018, the world population is around 7.6 billion, 4.2 billion in urban settlements and 3.4 billion in rural areas. Of this total, according to UN-Habitat, 3.2 billion of urban inhabitants live in southern countries. Of them, one billion, or nearly a thi ...

2019

Comparative analysis of time-based and quadrat sampling in seasonal population dynamics of intermediate hosts of human schistosomes

Andrea Rinaldo, Theophile Mande, Francisco Javier Perez Saez

Background Despite their importance for designing and evaluating schistosomiasis control trials, little attention in the literature has been dedicated to sampling protocols for the parasite's snail intermediate hosts since their first development. We propo ...

2019

A field-based modelling framework of the ecohydrology of schistosomiasis

Francisco Javier Perez Saez

Successful control of schistosomiasis, a water-borne parasitic disease, is challenged by the intricacy of the wormâ s lifecycle, which depends on aquatic snail intermediate hosts, and involves environmental, ecologic, and socio-economic factors. Current s ...

EPFL2018

Intestinal helminths modulate the gut microbiome

Alexis Rapin

Intestinal parasitic worms (commonly named intestinal helminths) affect close to one quarter of the world population and cause major losses for the livestock industry. These parasites establish chronic infections by modulation the immunity of their host. T ...

EPFL2018