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Brain-machine interfaces hold promise for restoring basic functions such as movement or speech for severely disabled patients, as well as for controlling neuroprosthetic devices for amputees. One of the major challenges of clinically viable neuroprostheses ...
Background: Total Ankle Replacement (TAR) o_ers the advantage of preserving ankle joint motion compared with ankle arthrodesis. However, compared to hip or knee arthroplasty, TAR is a less successful procedure when considering the relatively low implants s ...
This dissertation proposes a computational framework targeted at improving the design of currently employed retinal prostheses. The framework was used for analysing factors impacting the performance of prostheses in terms of electrical stimulation for reti ...
Lymphatic capillary drainage of interstitial fluid under both steady-state and inflammatory conditions is important for tissue fluid balance, cancer metastasis, and immunity. Lymphatic drainage function is critically coupled to the fluid mechanical propert ...
The primary stability of cementless femoral components is crucial for the long-term success of total hip arthroplasty. The mechanisms which influence this stability are not yet well understood. However, mechanical environment in peri-implant tissue is know ...
Since the introduction of implantable pacemakers in the early 1960s, implantable medical devices have become more and more interesting for healthcare services. Nowadays, the devices designed to monitor physiological data from inside the human body have gre ...
By delivering immunomodulatory drugs in vivo directly to lymph nodes draining an injection site, an opportunity exists to increase drug bioavailability to local immune cells. Importantly, particles smaller than 100 nm are efficiently transported through ly ...
Lymphatic vessels transport interstitial fluid, soluble Ag, and immune cells from peripheral tissues to lymph nodes (LNs), yet the contribution of peripheral lymphatic drainage to adaptive immunity remains poorly understood. We examined immune responses to ...
This paper provides a theoretical assessment of the safety considerations encountered in the simultaneous use of transcranial magnetic stimulation (TMS) and neurological interventions involving implanted metallic electrodes, such as electrocorticography. M ...
Cell organization into functional multicellular three-dimensional structures is a long-standing challenge. In particular, engineering of vascularized tissues requires both blood and lymphatic neovascular network formation in a simultaneous and coordinated ...
