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This lecture covers the properties of chromium, a metal widely used in various industries, its two oxidation states, and the impact of each on human health and the environment. It discusses the presence of chromium in tap water, its cycling in different environments, contamination issues, redox transformations, pathways of transformation, uptake and efflux mechanisms, reduction processes, detoxification strategies, and the resistance of some organisms to chromium. The lecture also explores the importance of harnessing natural processes for remediating chromium-contaminated sites, focusing on in situ microbial reduction as a potential solution.