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This lecture explores the concept of 'total war' from the 15th to the 20th century, emphasizing the role of science in warfare. It delves into the impact of inventions like gunpowder, printing, and the compass, and discusses the mobilization of science during the French Revolution and World War I. The lecture also examines the transformation of warfare through the 'totalization' process, highlighting key figures like Clausewitz and Bacon, and their influence on military strategies and tactics.