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This lecture provides a historical overview of genomics, starting with the development of Sanger sequencing in 1975, the race between public and private entities to sequence the human genome in 1990, and the contributions of Craig Venter in the mid-nineties. It also covers the challenges of shotgun sequencing, the assembly problem, and the revolutionary impact of high-throughput sequencing technologies. The lecture discusses the significant reduction in sequencing costs over the years and concludes with a glimpse into the future of genomics through the services offered by Nebula Genomics.