Probe Array Technology for Life Sciences

This lecture presents a project focused on developing probe array technology for life sciences, specifically for diagnosing cancer. The project involves two main approaches: probe arrays with tips to interact with cells and cantilever arrays for mechanical detection of cancer-related substances. The lecture details the process of functionalizing cantilevers with DNA or RNA to detect specific gene mutations related to melanoma. It also discusses the successful detection of circulating tumor cells using sensors and elasticity measurements to differentiate cancer stages. Additionally, the lecture covers the development of an electronic nose for detecting head and neck cancer through breath analysis, showcasing promising results in distinguishing cancer patients from healthy individuals.