DNA as Biomaterial Lecture: Programming with DNA Origami

This lecture covers the fundamentals of DNA, its structure, function, and properties, as well as DNA nano-engineering, bioengineering applications, and the use of DNA as a programmable biomaterial. Topics include DNA origami, synthesis, assembly, cell uptake, immune activation, and the engineering of various DNA structures. The lecture also explores the role of DNA in bioengineering, focusing on its potential in creating wireframe structures, lattice-based 3D origami, and more complex DNA particles. Additionally, it delves into the interaction of DNA with cells, discussing the challenges and strategies for delivering DNA-based materials into cells and the immune response. The lecture showcases the versatility of DNA as a biomaterial for various applications.