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This lecture covers the process of DNA replication, focusing on the mechanisms and enzymes involved. The instructor discusses the importance of primase, DNA polymerase, and ligase in replicating DNA strands, as well as the significance of leading and lagging strands. The lecture also delves into the concept of replication forks, the role of helicase in unwinding DNA, and the function of the replisome. Additionally, the discussion touches on the challenges faced during DNA replication, such as the need for accurate base pairing and the correction of errors by DNA polymerase. The instructor emphasizes the precision required in DNA replication to ensure the fidelity of genetic information.