Epigenetic Biomarkers of Traumata

This lecture explores the concept of epigenetics, focusing on DNA methylation, histone modifications, and their role in memory formation and trauma. It discusses the influence of the environment on gene expression, particularly in the brain, and how maternal care can impact epigenetic programming. The lecture delves into the use of HDAC inhibitors to overcome traumatic memories, highlighting their potential in altering enzymatic machinery and increasing histone acetylation. It also addresses the challenges in attenuating older memories and the identification of biomarkers for traumata. The importance of epigenetic clocks in aging and the potential for personalized medicine are also discussed.