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Lecture
Total Synthesis of Discodermolide
Description
This lecture covers the total synthesis of Discodermolide, a potent immunosuppressive and cytotoxic compound isolated from a Caribbean deep-sea sponge. The synthesis involves various steps such as olefin metathesis, boron aldol reaction, Suzuki cross-coupling, and reduction. Strategies by Novartis and A. B. Smith are discussed, along with historical milestones in the development of this compound.
Official source
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