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This lecture covers the design and analysis of experiments, focusing on comparison statistics. It starts with checking if an experimental factor affects a measured response, then delves into hypothesis testing methodologies like t-tests and ANOVA. The ANOVA methodology is explained, followed by an example of blood coagulation based on diet. The lecture also discusses ANOVA table generation, interpretation of F-ratio values, correlation analysis, and linear regression. Key topics include the Pearson correlation, coefficient of determination, and handling outliers in regression analysis.