Substitutions and Eliminations in Organic Chemistry

This lecture covers the importance of organic chemistry in everyday compounds, highlighting the work of Dorothy Hodgkin in determining the structures of key molecules like penicillin, vitamin B12, and insulin. It then delves into the mechanisms of SN1 and SN2 reactions, discussing factors influencing reaction pathways, stereochemistry, regioselectivity, and the role of bases and nucleophiles. The lecture also explores the synthesis of natural products like Nakijiquinone and Clopidogrel, emphasizing the impact of substrate structure, solvent choice, and base strength on reaction outcomes.