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This lecture covers the different ways animal cells can signal to each other, including endocrine, paracrine, neuronal, and contact-dependent signaling. It also explains the distinction between surface receptors and intracellular receptors, the action of protein and steroid hormones, and the genetic basis of red hair color. The lecture delves into the role of melanocytes in producing eumelanin and pheomelanin, the transfer of melanin to hair cells, and the melanosome transfer pathway. Additionally, it discusses the Mc1R receptor, the production of melanin in melanocytes, and the paracrine communication in a hair bulb, highlighting the importance of CAMP concentration in determining hair color.