Melanocytes and Hair Color Regulation

This lecture explores the role of paracrine communication in hair bulb melanocytes, focusing on the production of eumelanin and pheomelanin. It delves into the influence of CAMP concentration on hair color, the function of 7 transmembrane domain receptors, and the impact of Mc4R mutations on food intake and obesity. The lecture also discusses the evolutionary significance of hair color switches and fur phenotypes in mice, highlighting the complex interplay of genetic mutations and signaling pathways in determining hair color and body weight regulation.