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This lecture covers the passage of particles through matter, focusing on the LPM effect at high energies, muon energy loss, and radiative processes. It discusses the energy loss mechanisms for muons and pions in materials like iron, emphasizing the importance of radiative effects. The lecture also explains the average rate of muon energy loss and the contributions to energy loss by different processes. Additionally, it explores selected topics in nuclear and particle physics, such as solar neutrino mixing parameters and evidence for atmospheric neutrino oscillations.