DNA Repair: UV Damage and Skin Cancer

This lecture delves into the intricate process of DNA repair, focusing on UV-induced damage and its link to skin cancer. The instructor explains how UV radiation causes specific DNA lesions, leading to mutations that can accumulate over time and result in cancer. By exploring the repair mechanisms involved, such as nucleotide excision repair, the lecture highlights the importance of genetic factors in protecting against UV damage. The discussion extends to rare genetic disorders like Xeroderma Pigmentosum, shedding light on the critical role of DNA repair proteins in preventing mutations. Through real-life examples and scientific insights, the lecture emphasizes the significance of understanding DNA repair mechanisms in the context of mutation accumulation and cancer development.