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This lecture by the instructor from the University of Basel focuses on tracking and predicting the evolution of human RNA viruses, such as SARS-CoV and SARS-CoV-2. The presentation covers real-time tracking using Nextstrain, the diversity and spread of SARS-CoV-2, available data on virus mutations, and the phylogeny of different genotypes. It also discusses the dataset, phylogeny, and clades related to the viruses, highlighting the importance of understanding the mutations and frequencies to predict the evolution of these viruses.