Engineering Intelligent Cells

This lecture introduces the concept of engineering intelligent cells in the field of Synthetic Biology, focusing on the ultimate goal of cell engineering. It covers the functionalities needed to create intelligent cells, such as sensors, processing, and actuation. The lecture discusses the design of genetic and protein circuits for cell engineering, emphasizing the differences between them and their applications. It explores the challenges and advantages of using proteins in circuit design, including the ideal components for protein circuits. The lecture also delves into the sensing mechanisms for both extracellular and intracellular targets, highlighting the limitations of current sensing schemes and proposing solutions for more efficient signal transmission.