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This lecture covers the acid-base equilibrium, explaining the role of acids and bases in reactions, the concept of equilibrium constants, the behavior of water in reactions, buffer solutions, the Henderson-Hasselbalch equation, and titrations. It also discusses the preparation of buffer solutions, the calculation of pH in buffer solutions, and the equivalence point in titrations. The instructor demonstrates the calculation of pH in various scenarios and the importance of buffer solutions in maintaining pH stability.