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This lecture covers the pathogenesis and aetiology of Type I diabetes, focusing on the autoimmune destruction of insulin-producing cells and the role of genetic and environmental factors. It also discusses the sharp gradient in diabetes incidence between Russian Karelia and Finland, and the increasing incidence of Type I diabetes. The instructor explains the risk factors for Type II diabetes, including family history, obesity, and physical inactivity, and outlines various therapies such as healthy eating, exercise, and medication like Metformin and Sulfonylureas.
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