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This lecture discusses Persistent Organic Pollutants (POPs), focusing on their sources, such as Polycyclic Aromatic Hydrocarbons (PAHs) and pesticides, and their effects on the environment and living organisms. It covers the characteristics of POPs, their bioaccumulation potential, and their resistance to degradation. The lecture also explores the toxicity and carcinogenicity of PAHs, the replacement of chlorinated pesticides by organophosphorus pesticides, and the impact of POPs on human health. Additionally, it delves into the production, distribution, and exposure pathways of POPs, emphasizing the need for further research in this field.