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This lecture by Prof. Maurizio Corbetta delves into the relationship between brain lesions caused by stroke and resulting behavioral deficits, emphasizing the importance of network organization. By analyzing data from stroke patients, he explores how lesions in the white matter and basal ganglia impact cognitive and motor functions, highlighting the role of modularity in recovery. The talk also discusses the limitations of lesion symptom mapping and the need for computational models to better understand brain-behavior relationships. Prof. Corbetta suggests that future interventions should focus on restoring normal brain synchronization and organization to improve recovery outcomes.