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This lecture introduces the basics of programming with Python, focusing on practical aspects over theory. Topics include Python fundamentals, problem-solving skills, and efficient searching techniques. The course emphasizes hands-on learning and encourages self-reliance in coding. Students will explore Python's syntax, standard library, and tools for utilizing existing libraries. The instructor provides guidance on setting up Python and Visual Studio Code, both locally and on virtual machines. Additional support sessions are available for theoretical and programming aspects. The lecture covers the significance of programming as a structured communication technique with computers and its applications in various scientific fields.