Protein Design: Structure and Function

This lecture covers the design of proteins for specific functions, focusing on understanding protein structures and interactions. The instructor explains the challenges of verifying designed proteins and the importance of experimental validation through crystallography. The lecture also delves into the evolution of protein design techniques, emphasizing the use of hotspot binding sites to create strong protein-protein interactions. Additionally, the discussion touches on the advancements in designing protein circuits using deep learning and the differences between genetic and protein circuits. The instructor encourages students to grasp the concepts behind protein design and cell engineering, preparing them for problem-solving exercises similar to those covered in the lecture.