Publication

Transcriptional signatures of regulatory and toxic responses to benzo-[a]-pyrene exposure

Kristin Schirmer
2011
Journal paper

Abstract

Background: Small molecule ligands often have multiple effects on the transcriptional program of a cell: they trigger a receptor specific response and additional, indirect responses ("side effects"). Distinguishing those responses is important for understanding side effects of drugs and for elucidating molecular mechanisms of toxic chemicals.

Official source

https://infoscience.epfl.ch/record/170565?ln=en

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Transcriptional signatures of regulatory and toxic responses to benzo-[a]-pyrene exposure

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Mechanistic insights into AMP-activated protein kinase-dependent gene expression

Mitocellular communication: Shaping health and disease

A Dissection of Oligomerization by the TRIM28 Tripartite Motif and the Interaction with Members of the Krab-ZFP Family

Mechanistic insights into AMP-activated protein kinase-dependent gene expression

Mitocellular communication: Shaping health and disease

A Dissection of Oligomerization by the TRIM28 Tripartite Motif and the Interaction with Members of the Krab-ZFP Family