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Nanoparticles that activate complement in the absence of biological molecules are described. The nanoparticles are shown to specifically target antigen presenting cells in specifically in lymph nodes, without the use of a biological molecule for targeting. These particles are useful vehicles for delivering immunotherapeutics.
Li Tang, Lixia Wei, Yu Zhao, Xiaomeng Hu
Lambert Charles François Potin
Henning Paul-Julius Stahlberg, Thomas Hofer, Wei Xu