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Publication
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Work with us on data science and visualisation projects, and deploy your project as an app on top of Graph Search.
The mammalian cyclic dinucleotide 2', 3'-cGAMP is a potent inducer of innate immune responses produced upon detection of cytosolic DNA by cGAS. The mechanisms underlying the control of intracellular cGAMP levels remained unclear. In a new study, Eaglesham et al. identified poxins as 2', 3'-cGAMP-specific nucleases allowing immune evasion by viruses.
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