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Polarised three-dimensional cellular aggregates

Matthias Lütolf, Giuliana Rossi
2020
Patent
Abstract

Polarised three-dimensional cellular aggregates (or gastruloids) generated in vitro from one or more pluripotent stem cells are provided. Methods for obtaining polarised three-dimensional cellular aggregates and cells (e.g. progenitor cells and derivatives thereof) obtained from the polarised three-dimensional cellular aggregates are also provided.

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