An asymmetric synthesis of the 3,5-dihydroxycyclohexanone subunit of baconipyrones A and B, as well as that of the hydroxydiketone subunit of baconipyrones C and D ((-)-(4S,6S)-4,6-dimethyl-5-hydroxynonan-3,7-dione), is described. Key steps include sulfur dioxide-induced additions of enoxysilanes to 1,3-dioxy-1,3-dienes, followed by retro-ene desulfitations (retro-ene elimination of SO2).
Bruno Emanuel Ferreira De Sousa Correia, Casper Alexander Goverde
Bruno Emanuel Ferreira De Sousa Correia, Karla Montserrat Castro Gilabert, Basile Isidore Martin Wicky, Jue Wang
Henning Paul-Julius Stahlberg, Jasenko Zivanov