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In human anatomy, the mouth is the first portion of the alimentary canal that receives food and produces saliva. The oral mucosa is the mucous membrane epithelium lining the inside of the mouth. In addition to its primary role as the beginning of the digestive system, the mouth also plays a significant role in communication. While primary aspects of the voice are produced in the throat, the tongue, lips, and jaw are also needed to produce the range of sounds included in speech. The mouth consists of two regions, the vestibule and the oral cavity proper. The mouth, normally moist, is lined with a mucous membrane, and contains the teeth. The lips mark the transition from mucous membrane to skin, which covers most of the body. The mouth consists of two regions: the vestibule and the oral cavity proper. The vestibule is the area between the teeth, lips and cheeks. The oral cavity is bounded at the sides and in front by the alveolar process (containing the teeth) and at the back by the isthmus of the fauces. Its roof is formed by the hard palate at the front, and the soft palate at the back. The uvula projects downwards from the middle of the soft palate at its back. The floor is formed by the mylohyoid muscles and is occupied mainly by the tongue. A mucous membrane – the oral mucosa, lines the sides and under surface of the tongue to the gums, and lines the inner aspect of the jaw (mandible). It receives secretions from the submandibular and sublingual salivary glands. The lips come together to close the opening of the mouth, forming a line between the upper and lower lip. In facial expression, this mouth line is iconically shaped like an up-open parabola in a smile, and like a down-open parabola in a frown. A down-turned mouth means a mouth line forming a down-turned parabola, and when permanent can be normal. Also, a down-turned mouth can be part of the presentation of Prader–Willi syndrome. The teeth and the periodontium (the tissues that support the teeth) are innervated by the maxillary and mandibular nerves – divisions of the trigeminal nerve.